irritation Synonyms

discomfort vexation botheration soreness pique annoyance annoying excitation provocation aggravation innervation temper surliness tenderness testiness tingling torment touchiness peevishness smarting self-reproof persecution pest pesterer plague plaguing pricking prickliness inflammation psoriasis pudency rage resentment trial trituration snappishness nudnik discontentedness painfulness heat rash ill humor sleeplessness resentfulness irritatingly disgruntlement self-disgust snit pinprick hassle trouble