trouble Synonyms

inconvenience disquiet discommode sorrow disturb disturbance annoy put out harass upset pain distress difficulty adversity bother misery afflict affliction misfortune perturb disorder setback saddle sickliness shortcoming sadden rumpus scrape question questionableness rack rattle rigmarole rock roil roughen ruffle sickness situation nag struggle stumper subsidency suffering swage tease thing striving stress strife