acetoacetate
Noun
Meaning
acetoacetate (plural acetoacetates)
(organic chemistry) Any salt or ester of acetoacetic acid
Examples
Beta-hydroxybutyrate is a reduced form of acetoacetate, in which the ketone group is converted into an alcohol (or hydroxyl ) group (see illustration on the right).
Thereby fumarate (also a metabolite of the citric acid cycle) and acetoacetate (3-ketobutyroate) are liberated.
Ketones can be measured in the urine (acetoacetate) and blood (β-hydroxybutyrate).
The smell of acetoacetate and/or acetone in breath is a common feature in ketosis.
When compared with urine acetoacetate testing, capillary blood β-hydroxybutyrate determination can reduce the need of admission, shorten the duration of hospital admission and potentially reduce the costs of hospital care.