ACTH
Noun
Meaning
a hormone produced by the anterior pituitary gland that stimulates the adrenal cortex
Source: WordNetSynonyms
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Examples
ACTH influences steroid hormone secretion by both rapid short-term mechanisms that take place within minutes and slower long-term actions.
Adrenarche is independent of ACTH or gonadotropins and correlates with a progressive thickening of the zona reticularis layer of the cortex.
ACTH also stimulates lipoprotein uptake into cortical cells.
However, a concomitant increase was observed in potentially wasted tests including cortisol levels measured while on steroid treatment, and continued unnecessary ACTH measurement.
However, cases such as this urge cautious consideration of ectopic ACTH secretion in patients with many common tumor histologies.
Cushing’s disease (CD) is caused by a tumor of the pituitary corticotroph cells that secretes excess adrenocorticotropin (ACTH).