adenylyl
Noun
Meaning
adenylyl (plural adenylyls)
(organic chemistry) A functional group derived from adenosine monophosphate, also known as 5-adenylic acid
Synonyms
Phrases with the word
Examples
Adenylyl cyclase catalyzes the conversion of ATP to 3',5'-cyclic AMP Classes Class I The first class of adenylyl cyclases occur in many bacteria including E. coli.
Class II These adenylyl cyclases are toxins secreted by pathogenic bacteria such as Bacillus anthracis and Bordetella pertussis during infection.
Class III These adenylyl cyclases are the most familiar based on extensive study due to their important roles in human health.
Photoactivatable adenylyl cyclase (PAC) was discovered in E. gracilis and can be expressed in other organisms through genetic manipulation.
The two signal pathways are connected together by Ca 2+ -CaM, which is also a regulatory subunit of adenylyl cyclase and phosphodiesterase in the cAMP signal pathway.
In peripheral cells and tissues adenylyl cyclases appear to form molecular complexes with specific receptors and other signaling proteins in an isoform-specific manner.