Noun
a drug (trade name Zyloprim) used to treat gout and other conditions in which there is an excessive buildup of uric acid
Source: WordNetAdjunctive allopurinol is safe, effective, and well tolerated in inflammatory bowel disease patients who do not respond adequately to thiopurines due to hypermethylation. Source: Internet
Some practitioners advocate adding allopurinol only in people in whom hyperuricosuria and hyperuricemia persist, despite the use of a urine- alkalinizing agent such as sodium bicarbonate or potassium citrate. Source: Internet
Once the acute attack subsides, levels of uric acid can be lowered via lifestyle changes and in those with frequent attacks, allopurinol or probenecid provides long-term prevention. Source: Internet
Higher doses and rapid introduction of allopurinol and lamotrigine may also increase the risk of developing SJS/TEN. Source: Internet
Study 3, a 1 year study, randomized patients to: ULORIC 80 mg daily, ULORIC 120 mg daily, or allopurinol 300 mg daily. Source: Internet
Combining allopurinol with reduced doses of thiopurines promotes production of 6TGN over 6MMP, leading to optimal 6TGN concentrations and improved clinical benefit in hypermethylators, they explained. Source: Internet