Noun
amantadine (plural amantadines)
(pharmacology) A drug used especially as the hydrochloride C10H17N·HCl to prevent infection (as by an influenzavirus) by interfering with virus penetration into host cells.
Excessive glutamate activity is believed to be involved in catatonia; when first-line treatment options fail, NMDA antagonists such as amantadine or memantine are used. Source: Internet
Many strains of H5N1 influenza A, also known as avian influenza or "bird flu", have shown resistance to rimantadine and amantadine. Source: Internet
Memantine has a more targeted pharmacological profile for the glutamate system, reduced incidence of psychosis and may therefore be preferred for individuals who cannot tolerate amantadine. Source: Internet