Adjective
(chemistry) Describing a molecule, such as a detergent, which has both hydrophobic and hydrophilic groups.
(biochemistry) Of the surface(s) on a protein, particularly an alpha helix, where one surface of the alpha helix has hydrophilic amino acids and the opposite face has hydrophobic (or lipophilic) amino acids.
Source: en.wiktionary.orgPhospholipids and cholesterol, being amphipathic, are transported in the monolayer surface of the lipoprotein particle. Source: Internet
The glycerophospholipids are amphipathic molecules (containing both hydrophobic and hydrophilic regions) that contain a glycerol core linked to two fatty acid-derived "tails" by ester linkages and to one "head" group by a phosphate ester linkage. Source: Internet