analgesia
Noun
Meaning
Absence of sensibility to pain.
Source: Webster's dictionarySynonyms
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Analgesics Analgesics (also known as "painkillers") are used to relieve pain (achieve analgesia).
Both analgesia and drug addiction are functions of the mu opioid receptor, the class of opioid receptor first identified as responsive to morphine.
As such, in general, the idea of alcohol for analgesia is considered a primitive practice in virtually all industrialized countries today.
Endorphins, a contraction of the term endogenous morphines, are responsible for analgesia (reducing pain), causing sleepiness, and feelings of pleasure.
Episodic analgesia may occur under special circumstances, such as in the excitement of sport or war: a soldier on the battlefield may feel no pain for many hours from a traumatic amputation or other severe injury.
Dextromethorphan has been noted to slow the development of tolerance to opioids and exert additional analgesia by acting upon the NMDA receptors; some analgesics such as methadone and ketobemidone and perhaps piritramide have intrinsic NMDA action.