antisense
Noun
Meaning
antisense (plural antisenses)
(genetics) A molecule which interacts with a complementary strand of nucleic acids, so as to suppress its transcription.
Synonyms
Antonyms
Phrases with the word
Anagrams
Examples
A common reverse genetics technique is to reduce gene expression or modify splicing using Morpholino antisense technology.
Like all antisense approaches, different MOs can have different efficacy, and may cause off-target, non-specific effects.
An antisense structural type that has proven especially valuable in research is morpholino antisense.
Both sense and antisense sequences can exist on different parts of the same strand of DNA (i.e. both strands can contain both sense and antisense sequences).
Gene expression knockdown techniques The expression of genes can be reduced by a variety of means, for example by using antisense oligonucleotides targeting specific mRNA molecules.
Lee, J. T., Davidow, L. S., Warshawsky, D., (1999), Tisx, a gene antisense to Xist at the X-inactivation centre.