apolipoprotein
Noun
Meaning
English Wikipedia has an article on:apolipoproteinWikipedia
apolipoprotein (plural apolipoproteins)
(biochemistry) Any polypeptide or protein that can serve as an apoprotein by binding with a lipid to form a lipoprotein.
Examples
An example in humans is the apolipoprotein B mRNA, which is edited in some tissues, but not others.
Lipoprotein: These consist of a central core of a hydrophobic lipid (including TGs and cholesteryl esters) encased in a hydrophilic coat of polar phospholipid, free cholesterol and apolipoprotein.
Decreased HDL and apolipoprotein A-I (ApoA-l) levels in the general population are associated with an increased risk of death from cardiomyopathy and heart failure.
Niacin increases apolipoprotein A1 levels due to anti catabolic effects resulting in higher reverse cholesterol transport.
These defects are found in the FH genes, LDL receptor (LDLR), apolipoprotein B (APOB), proprotein convertase subtilisin/kexin type 9 (PCSK9), and possibly others.