ascorbate

Noun

Meaning

ascorbate (plural ascorbates)

(organic chemistry) Any salt or ester of ascorbic acid.

Synonyms

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Examples

Antioxidant mechanism Semidehydroascorbate acid radical The ascorbate ion is the predominant species at typical biological pH values. Source: Internet

At high dietary doses (corresponding to several hundred mg/day in humans) ascorbate is accumulated in the body until the plasma levels reach the renal resorption threshold, which is about 1.5 mg/dL in men and 1.3 mg/dL in women. Source: Internet

During biosynthesis ascorbate acts as a reducing agent, donating electrons and preventing oxidation to keep iron and copper atoms in their reduced states. Source: Internet

Severe diseases such as scurvy can result from defects in this hydroxylation, e.g., mutations in the enzyme prolyl hydroxylase or lack of the necessary ascorbate (vitamin C) cofactor. Source: Internet

However, being a good electron donor, excess ascorbate in the presence of free metal ions can not only promote but also initiate free radical reactions, thus making it a potentially dangerous pro-oxidative compound in certain metabolic contexts. Source: Internet

However, taking vitamin C in the form of sodium ascorbate and calcium ascorbate may minimize this effect. Source: Internet

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