bile acid
Noun
Meaning
any of the steroid acids generated in the liver and stored with bile
Source: WordNetSynonyms
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Examples
Epidemiologic studies have found that fecal bile acid concentrations are increased in populations with a high incidence of colon cancer.
Fatty acid bile acid conjugates (FABACs) have been found to affect skin by enhancing ATP-binding cassette (ABCA1) cholesterol transporter and competitively inhibiting stearoyl-CoA desaturase (SCD1) enzyme.
OCA, the compound that activated the bile acid receptor in this study, is approved for the treatment of primary biliary cirrhosis (Intercept Pharmaceuticals) offering fast translational opportunities for pharmacotherapies.
These include tests for hydrogen breath test, bile acid and D-xylose.
“(They) redefine the physiological significance of bile acid signaling and highlight the importance of determining whether bile acid analogues represent a viable pharmacological treatment for cocaine abuse.”
Therapeutic trials of these drugs are indicated in chronic diarrhea if bile acid malabsorption cannot be diagnosed with a specific test, such as SeHCAT retention.