Noun
BRCA1 (plural BRCA1s)
(biochemistry) A human tumor suppressor gene associated with breast cancer.
Expression of four key DNA repair genes that are necessary for homologous recombinational repair during meiosis (BRCA1, MRE11, Rad51, and ATM) decline with age in oocytes. Source: Internet
Actress and director Angelina Jolie had both her breasts and her ovaries removed after learning she carried the BRCA1 gene. Source: Internet
Such outcrossing events appear to be rare in L. major and L. donovani. citation L. infantum produces proteins BRCA1 and RAD51 that interact with each other to promote homologous recombinational repair. citation These proteins play a key role in meiosis. Source: Internet
The BRCA1 protein plays a key role in a type of DNA repair termed homologous recombinational repair that is the only known cellular process that can accurately repair DNA double-strand breaks. Source: Internet
The surgery is generally considered when the person has BRCA1 or BRCA2 mutations in their genes. Source: Internet
“There is an increased risk of pancreatic cancer in individuals who have inherited genetic mutations in certain genes, such as BRCA1 and BRCA2, more commonly associated with breast and ovarian cancers,” notes Dr. Frank. Source: Internet