Noun
Canavan disease (uncountable)
A degenerative disorder that causes progressive damage to nerve cells in the brain.
Pathophysiology Canavan disease has an autosomal recessive pattern of inheritance Canavan disease is inherited in an autosomal recessive fashion. Source: Internet
Mutation detection in the aspartoacylase gene in 17 patients with Canavan disease: four new mutations in the non-Jewish population. Source: Internet
The defective enzyme in Canavan disease, aspartoacylase, converts N-acetylaspartate into aspartate and acetate. Source: Internet
In 1987 the Greenbergs, a family with two children affected by Canavan disease, donated tissue samples to Reuben Matalon, a researcher at the University of Chicago who was looking for the Canavan gene. Source: Internet
Prevalence Although Canavan disease may occur in any ethnic group, it affects people of Eastern European Jewish ancestry more frequently. Source: Internet
Treatment There is no cure for Canavan disease, nor is there a standard course of treatment. Source: Internet