capsaicin
Noun
Meaning
A colorless crystalline substance extracted from the Capsicum annuum, and giving off vapors of intense acridity.
Source: Webster's dictionarySynonyms
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Biosynthesis History The general biosynthetic pathway of capsaicin and other capsaicinoids was elucidated in the 1960s by Bennett and Kirby, and Leete and Louden.
By binding to the TRPV1 receptor, the capsaicin molecule produces similar sensations to those of excessive heat or abrasive damage, explaining why the spiciness of capsaicin is described as a burning sensation.
Early research showed capsaicin to evoke a strikingly long-onset current in comparison to other chemical agonists, suggesting the involvement of a significant rate-limiting factor.
It is common for people to experience pleasurable and even euphoric effects from ingesting capsaicin.
They found that higher amounts of capsaicin were needed to produce coughs in the group treated with theobromine and that the theobromine proved more effective than codeine as a cough-supressant.
Bronchoconstrictor response to inhaled capsaicin in humans" J. Appl.