carboxyl group
Noun
Meaning
the univalent radical -COOH; present in and characteristic of organic acids
Source: WordNetSynonyms
Hypernyms
Examples
An α-amino acid has a central carbon (the α or alpha carbon ) which is covalently bonded to a carboxyl group (thus they are carboxylic acids ), an amino group, a hydrogen atom and a variable group.
Each fatty acid has a carboxyl group (–COOH).
At physiological pH, typically around 7, free amino acids exist in a charged form, where the acidic carboxyl group (-COOH) loses a proton (-COO − ) and the basic amine group (-NH 2 ) gains a proton (-NH 3 + ).
Calculating pI values For an amino acid with only one amine and one carboxyl group, the pI can be calculated from the mean of the pKas of this molecule.
It has two ionizable groups in the physiological range (the amino group in alpha-position to the amide carbonyl group and the carboxyl group).
Next, a glycine is incorporated fueled by ATP hydrolysis and the carboxyl group forms an amine bond to the NH 2 previously introduced.