CCR5

Noun

Meaning

CCR5 (countable and uncountable, plural CCR5s)

Initialism of C-C chemokine receptor type 5. (a coreceptor of CD4 receptor)

Phrases with the word

Examples

2. Conformational change in gp120 allows for secondary interaction with CCR5. Source: Internet

A mutation of the gene CCR5 gives some protection against HIV but leads to more serious complications of WNV infection. Source: Internet

Attempts to interfere with the binding of HIV with the CD4 receptor have failed to stop HIV from infecting helper T cells, but research continues on trying to interfere with the binding of HIV to the CCR5 receptor in hopes that it will be more effective. Source: Internet

The Berlin Patient is a man whose HIV infection seemed to be eradicated after he was given a bone marrow transplant from a CCR5 negative donor. Source: Internet

HIV can infect dendritic cells (DCs) by this CD4- CCR5 route, but another route using mannose-specific C-type lectin receptors such as DC-SIGN can also be used. citation DCs are one of the first cells encountered by the virus during sexual transmission. Source: Internet

One variant of CCR5, called CCR5 Δ32, is missing a particular string of 32 “letters” of DNA code. Source: Internet

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