CD4
Noun
Meaning
a glycoprotein that is found primarily on the surface of helper T cells
Source: WordNetSynonyms
Hypernyms
Examples
CD4 is a receptor for HIV in humans
All patients had stable or decreased viral load; four of the five patients had stable or increased CD4 T cell counts.
“AZD5582 was remarkable in its ability to reactivate latent SIV from resting CD4+ T cells, and to induce continued virus production in the blood when monkeys were still receiving daily antiretroviral therapy,” she said.
Another subset of the T cells — called CD4 T cells — help the B cell-antibody response become more efficient and long-lived, Rath noted, adding that these must be examined in order to understand the efficiency and longevity of antibody responses.
Attempts to interfere with the binding of HIV with the CD4 receptor have failed to stop HIV from infecting helper T cells, but research continues on trying to interfere with the binding of HIV to the CCR5 receptor in hopes that it will be more effective.
CD4 + T cell count (cells per µL) HIV RNA copies per mL of plasma Many HIV-positive people are unaware that they are infected with the virus.