CFTR

Noun

Meaning

the gene that is mutated in cystic fibrosis

Source: WordNet

Synonyms

cystic fibrosis transport regulator cftr function cystic fibrosis chloride pump cftr inhibitor cftr modulator cftr mutation cftr-associated diseases cftr-related disorders cftr knockout cftr localization cftr regulation cftr gene cftr trafficking cftr protein cftr-targeted therapy

Show all synonyms

Hypernyms

mutant gene

Phrases with the word

cftr function cftr inhibitor cftr modulator cftr mutation cftr-associated diseases cftr-related disorders

Examples

CF develops when neither allele can produce a functional CFTR protein. Source: Internet

CFTR not only allows chloride ions to be drawn from the cell and into the ASL, but it also regulates another channel called ENac, whichallows sodium ions to leave the ASL and enter the respiratory epithelium. Source: Internet

For example, cystic fibrosis is caused by mutations in the CFTR gene, and is the most common recessive disorder in caucasian populations with over 1,300 different mutations known. Source: Internet

It is caused by the presence of mutations in both copies of the gene for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Source: Internet

However, when the CFTR protein is malfunctioning, these ions cannot flow out of the cell due to a blocked channel. Source: Internet

If testing shows that parent is a CFTR gene mutation carrier, the other parent is tested to calculate the risk that their children will have CF. Source: Internet

Close letter words and terms

CFRP CFS CFT cftr activator cftr channel cftr dysfunction