chemokine

Noun

Meaning

chemokine (plural chemokines)

(biochemistry, immunology) Any of various chemotactic cytokines, produced during inflammation, that organize the leukocytes.

Source: en.wiktionary.org

Synonyms

cytokine lymphocyte interleukin macrophage chemocytokine cytochemokine eotaxin

Examples

HIV-1 entry to macrophages and CD4 + T cells is mediated through interaction of the virion envelope glycoproteins (gp120) with the CD4 molecule on the target cells and also with chemokine coreceptors. Source: Internet

HIV infects a cell through fusion with the cell membrane, which requires two different cellular molecular participants, CD4 and a chemokine receptor (differing depending on the cell type). Source: Internet

Once gp120 is bound with the CD4 protein, the envelope complex undergoes a structural change, exposing the chemokine binding domains of gp120 and allowing them to interact with the target chemokine receptor. Source: Internet

Similar to phosphorylated tyrosines, sulfated tyrosines are used for specific recognition, e.g., in chemokine receptors on the cell surface. Source: Internet

Close letter words and terms

chemoirradiation chemoirritant chemokinase chemokinemia chemokinesis chemokinetic