chloramphenicol
Noun
Meaning
an oral antibiotic (trade name Chloromycetin) used to treat serious infections (especially typhoid fever)
Source: WordNetSynonyms
Hypernyms
Examples
Intravenous The intravenous (IV) preparation of chloramphenicol is the succinate ester, because pure chloramphenicol does not dissolve in water.
Neurotoxic reactions Headache, mild depression, mental confusion, and delirium have been described in patients receiving chloramphenicol.
No difference in bioavailability is noted between chloramphenicol and CPE.
Currently, some Enterococcus faecium and Pseudomonas aeruginosa strains are resistant to chloramphenicol.
In liver impairment, the dose of chloramphenicol must therefore be reduced.
It is easy to select for reduced membrane permeability to chloramphenicol in vitro by serial passage of bacteria, and this is the most common mechanism of low-level chloramphenicol resistance.