cisplatin
Noun
Meaning
(pharmacology, uncountable) A platinum-containing antineoplastic drug cis-diamminedichloro-platinum(II) (Cl2H6N2Pt) that is cytotoxic and is used especially in the treatment of testicular and ovarian tumors and advanced bladder cancer.
(dated, countable) A platin, that is, a platinum-based antineoplastic, of which class cisplatin is the archetypal member.
Source: en.wiktionary.orgSynonyms
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Drugs with medium risk include doxorubicin and platinum analogs such as cisplatin and carboplatin.
If stage II or III disease is confirmed, adjuvant chemotherapy improves survival by 5% at five years. citation citation The combination of vinorelbine and cisplatin is more effective than older regimens.
Cisplatin is used to treat most solid tissue cancers including testicular, ovarian, colorectal, lung and breast cancers.
Merck said a Phase 3 study of its immuno-oncology drug Keytruda in tandem with chemotherapy drugs pemetrexed (Alimta) and cisplatin or carboplatin was successful.
When cisplatin is present, it is thought to be the most active single agent in periodic diseases. citation Advanced-stage tumors (IIB-IVA) are treated with radiation therapy and cisplatin-based chemotherapy.
Small-cell lung carcinoma (SCLC), even relatively early stage disease, is treated primarily with chemotherapy and radiation. citation In SCLC, cisplatin and etoposide are most commonly used.