Noun
a state of depression and anhedonia so severe as to require clinical intervention
Source: WordNetThe term clinical depression finds its way into too many conversations these days. One has a sense that a catastrophe has occurred in the psychic landscape. Leonard Cohen
I speak of a clinical depression that is the background of your entire life, a background of anguish and anxiety, a sense that nothing goes well, that pleasure is unavailable and all your strategies collapse. Leonard Cohen
Consequently, when I got to Toronto, much to my chagrin, I really couldn't handle hanging out with the American draft dodgers. There was too much clinical depression. Too much suicide. Too much hardcore substance abuse. They were a traumatized lot, those boys. And I just felt frivolous. William Gibson
Clinical depression takes two weeks to actually be diagnosed. Source: Internet