Noun
COMT (plural COMTs)
(biochemistry) Initialism of catechol-O-methyltransferase.
This has be postulated to be explained by variations of the gene which codes for the enzyme catechol-O-methyl transferase (COMT) which may produce 3 different phenotypes with regards pain sensitivity. Source: Internet
These create dopamine, which then experiences methylation by a catechol-O-methyltransferase (COMT) by an S-adenosyl methionine (SAM)-dependent mechanism. Source: Internet
The variation of the COMT gene which produces less of this enzyme is associated with a high sensitivity to pain. Source: Internet
It turns out that I am also homozygous for the COMT gene which means that I have an 80% decreased capacity to clear estrogen (thanks mom and dad!). Source: Internet
For some of our patients, one of the tests we do is looking for genetic predispositions as they relate to methylation, and one of those is COMT. Source: Internet