corneum
Noun
Meaning
the outermost layer of the epidermis consisting of dead cells that slough off
Source: WordNetSynonyms
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Although the stratum corneum (SC) is an efficient barrier, some substances are able to penetrate it to reach the underlying tissues and blood vessels.
It is a small film on the surface of the stratum corneum composed of fatty acids, lactic acid, pyrrolidine carboxylic acid, amino acids, and a bunch of other sciencey terms and stuff that can be a little overwhelming.
Here, N-arginine chitosan (N-Arg-CS) proved its potential as a novel transdermal enhancer, offering an alternative method to disrupt the molecular protein side-chains within the stratum corneum, in turn creating specific methods for enhancement.
Basal barrier function and stratum corneum integrity in different groups; integrity is measured as the number of tape strippings required to disrupt the barrier; modified from Reference 21.
In the present article, sunscreens containing the antioxidants vitamin E and diethylhexyl syringylidene malonate were tested for their efficacy in preventing UV-induced reactive oxygen species in the lower stratum corneum.
Most importantly, the skin’s barrier function to external penetration, as expressed by the water-handling properties of the stratum corneum (SC), appears to be weaker than an adult’s at first, and progressively matures over the first years of life.