creatinine
Noun
Meaning
English Wikipedia has an article on:creatinineWikipedia
creatinine (countable and uncountable, plural creatinines)
(biochemistry) A heterocyclic amine, 2-amino-1-methyl-5H-imidazol-4-one, formed by the metabolism of creatine.
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An initial workup of a patient may include a complete blood count (CBC); serum electrolytes including sodium, potassium, chloride, bicarbonate, calcium, and phosphorus; blood urea, nitrogen and creatinine ; blood glucose and glycocylated hemoglobin.
A moderate reduction in renal function, no greater than 30% rise in serum creatinine, that is stabilized after a week of treatment is deemed acceptable as part of the therapeutic effect, providing the residual renal function is sufficient.
After repeated dosing, the AUC was approximately tripled in patients with severe renal impairment (creatinine clearance < 20 mL/min).
If urinary riboflavin excretion is
Over time the BUN:Cr will decrease due to tubule epithelial damage. citation The increased nephron tubular pressure causes increased reabsorption of urea, elevating it abnormally relative to creatinine.
In clinical studies in renal artery stenosis and serum creatinine have been observed in some patients following ACE inhibitor therapy.