Noun
English Wikipedia has an article on:cyclinWikipedia
cyclin (plural cyclins)
(biochemistry) Any of a group of proteins whose presence in a cell varies through its cycle, and that regulates this cycle by forming a complex with kinase
After a CDK-cyclin complex has performed its function, the associated cyclin is polyubiquitinated and destroyed by the proteasome, which provides directionality for the cell cycle. Source: Internet
When activated by a bound cyclin, CDKs perform a common biochemical reaction called phosphorylation that activates or inactivates target proteins to orchestrate coordinated entry into the next phase of the cell cycle. Source: Internet
However, results from a recent study of E2F transcriptional dynamics at the single-cell level argue that the role of G1 cyclin-CDK activities, in particular cyclin D-CDK4/6, is to tune the timing rather than the commitment of cell cycle entry. Source: Internet