cyclization
Noun
Meaning
(chemistry) The process of cyclizing, of becoming or causing to become aromatic.
(chemistry) Any reaction that results in the formation of a ring. ring closure
Source: en.wiktionary.orgPhrases with the word
Examples
Bönnemann cyclization Bönnemann cyclization The trimerization of a part of a nitrile molecule and two parts of acetylene into pyridine is called Bönnemann cyclization.
It involves an aldol condensation of o-nitrobenzaldehyde with acetone, followed by cyclization and oxidative dimerization to indigo.
Synthesis The compound was originally prepared by Bernthsen in 1883 via the reaction of diphenylamine with sulfur, but more recent syntheses rely on the cyclization of 2-substituted diphenyl sulfides.
It lacks the NH 2 group because of the cyclization of the side-chain and is known as an imino acid ; it falls under the category of special structured amino acids.
In Bergman cyclization the reactants are an enyne plus a hydrogen donor.
Unsaturated fatty acids can serve as the olefinic substrates for the ene reaction and unsaturated amino acids like histidine can be the reactant for the Diels–Alder cyclization.