deprotonation
Noun
Meaning
English Wikipedia has an article on:deprotonationWikipedia
deprotonation (countable and uncountable, plural deprotonations)
(chemistry) The removal of a proton (hydrogen ion) from a molecule to form a conjugate base.
Examples
An ammine ligand bound to a metal ion is markedly more acidic than a free ammonia molecule, although deprotonation in aqueous solution is still rare.
It is this deprotonation that allows the serine side chain to act as a nucleophile and bind to the electron-deficient carbonyl carbon of the protein main chain.
The deprotonation reaction to produce an alkoxide salt is performed either with a strong base such as sodium hydride or n-butyllithium or with sodium or potassium metal.
The five-membered ring also possesses a keto group (in the 8 position), flanked by two secondary amino groups (in the 7 and 9 positions), and deprotonation of one of these at high pH could explain the pK 2 and behavior as a diprotic acid.
The C–H bonds adjacent to the carbonyl are weakly acidic but undergo deprotonation with strong bases.
The next step, formation of the double bond, takes place with elimination of a proton ( deprotonation ).