1. despond - Noun
2. despond - Verb
To give up, the will, courage, or spirit; to be thoroughly disheartened; to lose all courage; to become dispirited or depressed; to take an unhopeful view.
Despondency.
Source: Webster's dictionaryThe name of the Slough was Despond. John Bunyan
If fortune favors you do not be elated; if she frowns do not despond. Ausonius
Inaction will cause a man to sink into the slough of despond and vanish without a trace. Farley Mowat
The supporters of the Presidential candidate desponded when they learned the early results of the election Source: Internet