Noun
English Wikipedia has an article on:DNA ligaseWikipedia
DNA ligase (plural DNA ligases)
(biochemistry) Any of several enzymes that repair single-stranded discontinuities in double-stranded DNA
DNA ligase is used in both DNA repair and DNA replication (see Mammalian ligases ). Source: Internet
It plays a role in repairing single-strand breaks in duplex DNA in living organisms, but some forms (such as DNA ligase IV ) may specifically repair double-strand breaks (i.e. a break in both complementary strands of DNA). Source: Internet
It can also ligate blunt-ended DNA with much greater efficiency than E. coli DNA ligase. Source: Internet
Single-strand breaks are repaired by DNA ligase using the complementary strand of the double helix as a template, citation with DNA ligase creating the final phosphodiester bond to fully repair the DNA. Source: Internet
This step cuts out the DNA transposon, which is then ligated into a new target site; the process involves activity of a DNA polymerase that fills in gaps and of a DNA ligase that closes the sugar-phosphate backbone. Source: Internet