efavirenz
Noun
Meaning
efavirenz (uncountable) (abbreviated EFV)
(pharmacology) A nonnucleoside reverse-transcriptase inhibitor C14H9ClF3NO2 that is administered orally with other antiretroviral agents in the treatment of type-1 HIV infection.
Synonyms
Examples
Administration of efavirenz tablets with a high-fat meal increased the mean AUC and Cmax of efavirenz by 28% and 79%, respectively, compared to administration in the fasted state.
Because the risks of low-level exposure to efavirenz, emtricitabine, and tenofovir to infants are unknown, and because of the potential for HIV-1 transmission, mothers should be instructed not to breastfeed if they are receiving ATRIPLA.
From Weeks 96 to 144 of the trial, subjects received TRUVADA with efavirenz in place of emtricitabine + tenofovir DF with efavirenz.
Cholesterol and triglyceride levels fell after starting treatment in the doravirine arm, while rising in the efavirenz arm.