ESBL
Noun
Meaning
ESBL (plural ESBLs)
(medicine, biochemistry, microbiology) Initialism of extended-spectrum beta-lactamase.
Anagrams
Examples
Amino acid substitutions in OXA enzymes can also give the ESBL phenotype.
Plasmids responsible for ESBL production frequently carry genes encoding resistance to other drug classes (for example, aminoglycosides).
The amino acid substitutions responsible for the extended-spectrum beta lactamase (ESBL) phenotype cluster around the active site of the enzyme and change its configuration, allowing access to oxyimino-beta-lactam substrates.