Noun
English Wikipedia has an article on:excitotoxicityWikipedia
excitotoxicity (uncountable)
The continuous stimulation of a nerve cell by a neurotransmitter, especially by glutamates
Domoic acid has a very strong affinity for these receptors, which results in excitotoxicity initiated by an integrative action on ionotropic glutamate receptors at both sides of the synapse blocking the channel from rapid desensitization. Source: Internet
In addition there is a synergistic effect with endogenous glutamate and N-Methyl-D-aspartate receptor agonists that contribute to the excitotoxicity. Source: Internet
Excessive glutamate release can overstimulate the brain and lead to excitotoxicity causing cell death resulting in seizures or strokes. Source: Internet