Noun
FADD (uncountable)
Acronym of Fas-associated protein with death domain: an adaptor protein that bridges members of the tumor necrosis factor receptor superfamily, such as the Fas-receptor, to procaspases 8 and 10, to form the death-inducing signaling complex (DISC) during apoptosis.
Several caspases, in addition to APAF-1 and FADD, have been mutated to determine the new phenotype. Source: Internet
The interaction between Fas and FasL results in the formation of the death-inducing signaling complex (DISC), which contains the FADD, caspase-8 and caspase-10. Source: Internet