Noun
an amino acid that is found in the central nervous system; acts as an inhibitory neurotransmitter
Source: WordNetAn example of a receptor agonist is Valium, a benzodiazepine that mimics effects of the endogenous neurotransmitter gamma-aminobutyric acid (GABA) to decrease anxiety. Source: Internet
But a study of autistic children found it helps nerve cells communicate by correcting an imbalance between the brain's chemical messengers 'GABA' and 'glutamate'. Source: Internet
Because of this consistency, it is common for neuroscientists to simplify the terminology by referring to cells that release glutamate as "excitatory neurons", and cells that release GABA as "inhibitory neurons". Source: Internet
Expression of the GABA B R2 subunit alone, meanwhile, leads to surface expression of the subunit, although with no functional activity (i. Source: Internet
Both of the metabolic breakdown pathways shown for GHB can run in either direction, depending on the concentrations of the substances involved, so the body can make its own GHB either from GABA or from succinic semialdehyde. Source: Internet
However, at therapeutic doses, GHB reaches much higher concentrations in the brain and activates GABA B receptors, which are primarily responsible for its sedative effects. citation GHB's sedative effects are blocked by GABA B antagonists. Source: Internet