Noun
the largest city in Missouri; a busy river port on the Mississippi River near its confluence with the Missouri River; was an important staging area for wagon trains westward in the 19th century
Source: WordNetSome have questioned whether St. Louis really was—as Saarinen said —the "Gateway to the West". Source: Internet
The city was founded along the Missouri River, and a crossing called Lone Tree Ferry earned the city its nickname, the "Gateway to the West". Source: Internet