Noun
glecaprevir (uncountable)
(pharmacology) A protease inhibitor used to treat hepatitis C.
Combinations of NS3 Y56H plus D/Q168 substitutions resulted in greater reductions in glecaprevir susceptibility. Source: Internet
In HCV replicon assays, glecaprevir had median EC values of 0.08-4.6 nM against laboratory and clinical isolates from subtypes 1a, 1b, 2a, 2b, 3a, 4a, 4d, 5a, and 6a. Source: Internet
Maternal systemic exposure (AUC) to glecaprevir and pibrentasvir was approximately 47 or 74 times the exposure in humans at the RHD. Source: Internet