GM-CSF
Noun
Meaning
GM-CSF
(biochemistry) Initialism of granulocyte-macrophage colony-stimulating factor.
Examples
Three CSFs are granulocyte-macrophage CSF (GM-CSF), granulocyte CSF (G-CSF) and macrophage CSF (M-CSF). citation These stimulate granulocyte formation and are active on either progenitor cells or end product cells.
It was proposed that GM-CSF caused dendritic cells to present antigen more efficiently and enhance IL-2 production and TH cell activation, thus driving the increased immune response.
Mixing plasmids encoding GM-CSF and the circumsporozoite protein of P. yoelii (PyCSP) enhanced protection against subsequent challenge (whereas plasmid-encoded PyCSP alone did not).