Noun
GnRH
Initialism of gonadotropin-releasing hormone.
Finally, increasing levels of testosterone through a negative feedback loop act on the hypothalamus and pituitary to inhibit the release of GnRH and FSH/LH, respectively. Source: Internet
Hyperinsulinemia increases GnRH pulse frequency, LH over FSH dominance, increased ovarian androgen production, decreased follicular maturation, and decreased SHBG binding. Source: Internet
Using the GN11 cell model, which is considered a pre-migratory GnRH neuronal cell line, we demonstrated that GnRH-(1-5) inhibits cellular migration in a wound closure assay by binding the orphan G protein-coupled receptor 173 (GPR173). Source: Internet
With an anticipated May launch, TRELSTAR(R) 22.5 mg is the first and only six-month intramuscular (IM) GnRH agonist available for the palliative treatment of advanced prostate cancer. Source: Internet
Women with PCOS experience an increased frequency of hypothalamic GnRH pulses, which in turn results in an increase in the LH/FSH ratio. citation A majority of women with PCOS have insulin resistance and/or are obese. Source: Internet
GnRH antagonists have been used for the treatment of prostate cancer. Source: Internet