Noun
the first largest innermost toe
Source: WordNetAbout two o'clock in the morning he is awakened by a severe pain in the great toe; more rarely in the heel, ankle or instep. Source: Internet
Eighth tale (VII, 8) A husband grows jealous of his wife, and discovers that she has warning of her lover's approach by a piece of pack-thread, which she ties to her great toe at nights. Source: Internet
Gout may be diagnosed and treated without further investigations in someone with hyperuricemia and the classic acute arthritis of the base of the great toe (known as podagra). Source: Internet