Verb
(baseball) To hit a ball during an at-bat that results in all runners on base and the hitter scoring runs; the best result of an at-bat.
(figuratively) To achieve the best possible result.
(colloquial) To engage in genital intercourse.
(The addition of quotations indicative of this usage is being sought:)
I had only one superstition. I made sure to touch all the bases when I hit a home run. Babe Ruth
After I hit a home run I had a habit of running the bases with my head down. I figured the pitcher already felt bad enough without me showing him up rounding the bases. Mickey Mantle
Hit a home run - put your head down, drop the bat, run around the bases, because the name on the front is more - a lot more important than the name on the back. Ryne Sandberg
Somebody once asked me if I ever went up to the plate trying to hit a home run. I said, 'Sure, every time.' Mickey Mantle
You can make something big when young that will carry you through life. Look at all the big startups like Microsoft, Apple, Google, Facebook, Twitter, etc. They were all started by very young people who stumbled on something of unseen value. You'll know it when you hit a home run. Steve Wozniak
I loved to make a great defensive play, I'd rather do that than hit a home run. Bill Dickey