homeodomain
Noun
Meaning
English Wikipedia has an article on:homeodomain foldWikipedia
homeodomain (plural homeodomains)
(biochemistry, genetics) A folded protein domain that binds to DNA and has a function in transcription
Examples
Retinoic acid has its effects by turning on a differential pattern of Hox genes which encode different homeodomain transcription factors which in turn can turn on cell type specific genes.
Plants As in animals, the plant homeobox genes code for the typical 60 amino acid long DNA-binding homeodomain or in case of the TALE (three amino acid loop extension) homeobox genes for an "atypical" homeodomain consisting of 63 amino acids.
Such complexes have a much higher target specificity than a single homeodomain protein.
The homeodomain binds DNA in a sequence-specific manner.