huntingtin
Noun
Meaning
English Wikipedia has an article on:huntingtinWikipedia
huntingtin (countable and uncountable, plural huntingtins)
(biochemistry) A protein whose polymorphism is associated with Huntington's disease.
Examples
Expansion of CAG ( cytosine adenine guanine ) triplet repeats in the gene coding for the Huntingtin protein results in an abnormal protein, which gradually damages cells in the brain, through mechanisms that are not fully understood.
The Huntingtin gene provides the genetic information for a protein that is also called "huntingtin".
When the length of this repeated section reaches a certain threshold, it produces an altered form of the protein, called mutant Huntingtin protein (mHTT).