hypermethylation
Noun
Meaning
hypermethylation (countable and uncountable, plural hypermethylations)
(genetics) an increase in the epigenetic methylation of cytosine and adenosine residues in DNA.
Antonyms
Examples
Adjunctive allopurinol is safe, effective, and well tolerated in inflammatory bowel disease patients who do not respond adequately to thiopurines due to hypermethylation.
It can actually promote healthy epigenetic methylation, as well as inhibit the process of hypermethylation at those regions, at those suppressor gene sites.
Hypermethylation of the promoters between gene pairs WNT9A/CD558500, CTDSPL/BC040563, and KCNK15/BF195580 has been associated with tumors.