Noun
English Wikipedia has an article on:integrinWikipedia
integrin (plural integrins)
(biochemistry) Any of many heterodimeric transmembrane proteins that function as receptors in communication between cells.
Activation When released into the cell membrane, newly synthesized integrin dimers are speculated to be found in the same "bent" conformation revealed by the structural studies described above. Source: Internet
Gene knockouts of integrins in mice are not always lethal, which suggests that during embryonal development, one integrin may substitute its function for another in order to allow survival. Source: Internet
The molecular mass of the integrin subunits can vary from 90 kDa to 160 kDa. Source: Internet
Nevertheless, these so-called LIBS (Ligand-Induced-Binding-Sites) antibodies unequivocally show that dramatic changes in integrin shape routinely occur. Source: Internet
Plasma membrane-initiated actions begin at a receptor on the integrin alphaV beta3 that activates ERK1/2. Source: Internet
The integrin structure has drawn attention to this problem, which may have general implications for how membrane proteins work. Source: Internet