Adverb
In an irreversible manner.
Source: Webster's dictionaryIf we choose the path of destruction, the planet will continue to descend irreversibly into the Anthropocene Epoch, the biologically final age in which the planet exists almost exclusively by, for, and of ourselves. E. O. Wilson
Being in public with May and the children was too heavy. I was irreversibly tuned in to everyone around us. Sammy Davis, Jr.
They knew me wherever I went. Through the press, the name Eichmann had emerged as a symbol.... In any case, the word Jew ... was irreversibly linked with the word Eichmann. Much more power ... was attributed to me than I actually had. Adolf Eichmann
Collective human actions are transforming, even ravaging, the biosphere - perhaps irreversibly - through global warming and loss of biodiversity. Martin Rees
The global community has become irreversibly interdependent, with the constant movement of people, ideas, goods and resources. Mohamed ElBaradei
Freedom of speech is, to all Americans, as oxygen is to the human condition. It is a right that has been irreversibly programmed into our hard drive. We are free to speak our minds. An artist's right to express him or herself as best suits their art, is the artist's prerogative and it is guaranteed. John C. McGinley