isoelectric point
Noun
Meaning
isoelectric point (plural isoelectric points)
(physics, chemistry) the pH of a colloidal suspension or of an ampholyte at which the solute does not move in an electrophoretic field; symbol pI
Examples
Glycine may exist as a zwitterion at the isoelectric point, but the equilibrium constant for the isomerization reaction in solution :H 2 NCH 2 CO 2 H ⇌ H 3 N + CH 2 CO 2 − is not known.
Examples In these two examples the isoelectric point is shown by the green vertical line.
In the case that there is one species of each type, the isoelectric point can be obtained directly from the pK values.
Zwitterions have minimum solubility at their isoelectric point and some amino acids (in particular, with non-polar side-chains) can be isolated by precipitation from water by adjusting the pH to the required isoelectric point.