isoniazid
Noun
Meaning
antibacterial drug (trade name Nydrazid) used to treat tuberculosis
Source: WordNetSynonyms
Hypernyms
Examples
About 16 per cent of the estimated 480,000 new global cases of multidrug-resistant TB (patients who do not respond to the two anti-TB drugs isoniazid and rifampin) are from India, the editorial stated.
A newer regimen, basically a combination of isoniazid with rifapentine, has showed less liver toxicity and is required to be taken for only three months.
In 1952 (before Lurie and Salzer), Delay, with the resident Jean-Francois Buisson, reported the positive effect of isoniazid on depressed patients. citation The mode of antidepressant action of isoniazid is still unclear.
Line Probe Assays (LPAs) have 98% sensitivity and 99% specificity for rifampicin resistance, Isoniazid (INH) sensitivity always tends to be lower 84% and specificity is 99%.
In 1952, learning of the stimulating side effects of isoniazid, the Cincinnati psychiatrist Max Lurie tried it on his patients.
Since then, drugs such as isoniazid and rifampin have been used.